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Greektown Detroit is a historic commercial and entertainment district in Detroit, Michigan, located just northeast of the heart of downtown, along Monroe Avenue between Brush and St. Antoine streets. It has a station by that name on the city's elevated downtown transit system known as the Detroit People Mover. Greektown is situated between the Renaissance Center, Comerica Park, and Ford Field. 

Named for the historic Greek immigrant community of the early 20th century, the district still has Greek-themed restaurants. Notable buildings include St. Mary Roman Catholic Church (originally built for the former ethnic German congregation of the parish), Second Baptist Church, the Atheneum Suite Hotel, and the contemporary Greektown Casino-Hotel within its boundaries. The district was listed on the National Register of Historic Places in 1982. The district is often the site of the Greek community parade in March.

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